| Children |
| | 1. Janet Ruthven d. 9 Dec 1593, Edinburgh, Midlothian, Scotland  |
| | 2. James Ruthven of Fortevoit, b. 1521, Aberdeenshire, Scotland d. 9 Jan 1553, Scotland (Age 32 years) |
| | 3. Lady Christina Ruthven, of Ballindean, b. Abt 1532, Perth, Perthshire, Scotland, United Kingdom d. Jan 1574, Lower Largo, Fife, Scotland (Age ~ 42 years) |
| | 4. Lilias Ruthven, Baroness Drummond, b. 27 Jan 1526, Perth, Perthshire, Scotland d. 7 Jul 1579, Stobhall, Perthshire, Scotland (Age 53 years) |
| | 5. Alexander Ruthven, of Freeland, b. 1533, Kinnaird, Perthshire, Scotland d. 9 Oct 1599, Forgandenny, Perthshire, Scotland (Age 66 years) |
| | 6. Patrick Ruthven, 3rd Lord, Provost of Perth, b. 1520, Ruthven Castle, Perthshire, Scotland d. 13 Jun 1566, Newcastle upon Tyne, Northumberland, England (Age 46 years) |
| | 7. Lady Katherine Ruthven, Baroness Campbell, Countess of Craufurd, b. Abt 1530, Ruthven Castle, Perthshire, Scotland d. Sep 1580, Glenorchy, Argyll, Scotland (Age ~ 50 years) |
| | 8. Barbara Ruthven, b. 7 May 1535, Ruthven Castle, Perthshire, Scotland d. 21 Jul 1594, Perthshire, Scotland (Age 59 years) |
| | 9. Cecilia Ruthven, Lady of Wemyss, b. 7 May 1540, Kinnaird, Perthshire, Scotland d. 8 Jul 1589, Perthshire, Scotland (Age 49 years) |
|
1500 - 1552 (52 years)
